Sir.—I read with great interest the article by Lee et al in the April issue of the Journal (127:530, 1974). Looking back 37 years, Hess et al studied the urinary excretion of gonadotropic hormone (pregnancy urine extract) in unilateral and bilateral cryptorchid boys.1,2 They found that in some instances of bilateral cryptorchidism, there was an increased excretion of gonadotropic hormone, which indicated to us that there was either anorchidism or "compromised testicular function" in the presence of a physiologically active pituitary gland. As I no longer have access to the original articles nor reprints, I am unable to supply further details of the study. However, if Dr. Lee and his co-workers are interested, they may wish to read the articles.
KUNSTADTER RH. Serum Gonadotropins in Cryptorchidism. Am J Dis Child. 1974;128(6):888. doi:10.1001/archpedi.1974.02110310136035