An 11-month-old girl had systemic lupus erythematosus with a widespread skin rash. She manifested five of the criteria necessary for the diagnosis: oral ulcerations, alopecia, positive lupus erythematosus preparations, convulsions, and thrombocytopenia with leukopenia. Direct immunofluorescence showed deposits of IgG and C3 at the dermoepidermal junction of both abnormal and clinically uninvolved skin, and in subepithelial deposits along the glomerular basement membrane.
Grossman J, Schwartz RH, Callerame ML, Condemi JJ. Systemic Lupus Erythematosus in a 1-Year-Old Child. Am J Dis Child. 1975;129(1):123-125. doi:10.1001/archpedi.1975.02120380093022