February 1975

Lactogenic Hormones, Fetal Nutrition, and Lactation

Author Affiliations

The Children's Hospital of Pittsburgh 125 DeSoto St Pittsburgh, PA 15213


edited by John B. Josimovich, 483 pp, with illus, John Wiley & Sons Inc, 1974.

Am J Dis Child. 1975;129(2):266. doi:10.1001/archpedi.1975.02120390086027

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In 1962 when John B. Josimovich, MD, was a postdoctoral fellow, he published a fundamental paper on human placental lactogen. Interest in the function and characterization of the peptide grew rapidly. More recently, it was established that human pituitary prolactin (P) exists apart from pituitary growth hormone (GH), and elucidation of its role is progressing. According to our current understanding, the placentally produced placental lactogen, now termed "chorionic somatomammotropin" (CS), directs maternal metabolism to ensure fetal nutrition. Postpartum P production is required for lactation, and thereby plays an integral role in nutrition of the neonate. Because nutrition of the fetus and neonate commands the attention of both pediatric investigators and practicing pediatricians, the volume Lactogenic Hormones, Fetal Nutrition, and Lactation deserves the attention of both groups.

The book successfully presents recent discoveries in the basic biology of CS and P and their clinical applications. The chapters are by eminent basic

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