• Thirty-four patients with life-threatening childhood status asthmaticus were treated with intravenous isoproterenol infusions. Twenty-seven responded favorably; seven failed to respond and underwent mechanical ventilation.
Intravenously administered isoproterenol was a useful therapeutic adjunct in the treatment of these severe attacks. Complications in these cases were rare, but cardiac arrhythmia, rebound bronchospasm, and acute mobilization of secretions need to be considered. Further evaluation of the efficacy of intravenous infusions of isoproterenol in status asthmaticus would be valuable.
(Am J Dis Child (130:39-42, 1976)
Parry WH, Martorano F, Cotton EK. Management of Life-Threatening Asthma With Intravenous Isoproterenol Infusions. Am J Dis Child. 1976;130(1):39–42. doi:10.1001/archpedi.1976.02120020041006