• An 18-month-old boy developed meningitis due to group A β-hemolytic Streptococcus. Despite adequate antibiotic therapy with aqueous sodium penicillin G and chloramphenicol for more than eight weeks, he showed persistent abnormal spinal fluid findings, recurrent elevations of temperature, irritability, and poor feeding.
Further investigation revealed a congenital dermal sinus of the nose, with an entry into the anterior fossa that made a small opening intradurally at the level of the cribiform plate. Surgical removal of the entire sinus tract resulted in a speedy and complete recovery.
(Am J Dis Child 130:214-215, 1976)
Shadravan I, Fishbein J, Hebert LJ. Streptococcal Meningitis With an Unusual Port of Entry. Am J Dis Child. 1976;130(2):214-215. doi:10.1001/archpedi.1976.02120030104021