October 1976

Mucocutaneous Lymph Node Syndrome

Author Affiliations

Department of Pediatrics Mercy Hospital 301 St Paul PI Baltimore, MD 21202; Department of Pediatrics St Agnes Hospital 900 Caton Ave Baltimore, MD 21229

Am J Dis Child. 1976;130(10):1164. doi:10.1001/archpedi.1976.02120110126025

Sir.—Cases of mucocutaneous lymph node syndrome (MLNS) appearing in Arizona, California, Florida, Hawaii, Iowa, New York, Tennessee, and Washington, DC, have been reported to the Center for Disease Control.1 We have recently observed a patient in Maryland whose clinical course was consistent with the criteria accepted for MLNS.1-6

Report of a Case.—During October 1975, a 19-month-old boy developed a high fever that persisted for 15 days despite penicillin and erythromycin therapy. A generalized maculopapular rash accompanied by pharyngeal inflammation and cervical adenitis appeared two days after the onset of the fever. At the time of hospitalization on the 13th day of illness, a temperature of 40 C, bilateral conjunctivitis, generalized lymphadenopathy, oropharyngeal erythema, a scarlatiniform rash, and desquamation of the fingertips and toes were noted. Throat and nasal cultures showed normal flora. The WBC count was 14,400/cu mm, with 62% granulocytes. Corticosteroid therapy (used in the

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