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November 1976

Erythrocyte Survival in Children as Studied by Labeling With Stable 50Cr

Author Affiliations

From the departments of anatomical sciences (Dr Glomski) and nuclear science and technology (Dr Pillay), State University of New York at Buffalo, and the Children's Hospital, Buffalo, NY (Dr Macdougall). Dr Pillay is now with the Department of Nuclear Engineering, Pennsylvania State University, University Park. Dr Macdougall is now with the Department of Pediatrics, University of Witwatersrand, Johannesburg, South Africa.

Am J Dis Child. 1976;130(11):1228-1230. doi:10.1001/archpedi.1976.02120120062010

• The survival of 50Cr- and 51Cr-labeled autologous and/or homologous erythrocytes was compared simultaneously in eight pediatric patients and one adult. 50Cr, a stable, nonradioactive nuclide, had values comparable to those of standard radioactive 51Cr labeling. The data also demonstrated the capability of 50Cr-51Cr labeling to reveal differences in survival between two populations of erythrocytes monitored simultaneously in the same individual. The technique permitted the use of the nonradioactive isotope in volumes of blood that are appropriate for the pediatric age group.

(Am J Dis Child 130:1228-1230, 1976)