September 1977

Salmonella typhi Meningitis in a Neonate

Author Affiliations

Department of Pediatrics Division of Infectious Disease Children's Memorial Hospital 2300 Children's Plaza Chicago, IL 60614

Am J Dis Child. 1977;131(9):1031. doi:10.1001/archpedi.1977.02120220097017

Salmonella is a relatively rare, but noteworthy cause of purulent meningitis in infancy. At one time, the prognosis for infants with salmonella meningitis was thought to be uniformly poor,1,2 but recently a number of cases involving successfully treated patients have been reported.3-6 We are reporting a case of Salmonella typhi meningitis in a 3-week-old infant who was treated successfully with ampicillin sodium and gentamicin hydrochloride.

Report of a Case.—An infant, aged 3 weeks, was healthy until one day prior to admission to the hospital when he became irritable and somewhat lethargic. The next day a fever of 39.6 C developed. There was no history of vomiting, diarrhea, or seizures, and the infant was feeding well. The pregnancy was unremarkable, and delivery was by repeat cesarean section, but was otherwise uneventful. The birth weight was 4,075 gm. The infant was discharged from the nursery at 8 days of

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