November 1977

Hypothyroidism Due to Ectopy in Siblings

Author Affiliations

From the Institute of Pediatric and Adolescent Endocrinology (Drs Kaplan, Kauli, and Laron) and the Department of Nuclear Medicine (Dr Lubin), Beilinson Medical Center, Petah Tikva; the Department of Pediatrics, Yaffo Government Hospital (Dr Raviv); and the Sackler School of Medicine, Tel Aviv (Israel) University. Dr Laron is an Established Investigator of the Chief Scientist's Bureau, Ministry of Health, Israel.

Am J Dis Child. 1977;131(11):1264-1265. doi:10.1001/archpedi.1977.02120240082018

• Two families each had two siblings with hypothyroidism due to ectopy and hypoplasia of the thyroid. A genetic factor controlling normal thyroid development and descent may be responsible, and the importance of plasma thyroid-stimulating hormone estimation in borderline hypothyroid cases is emphasized. We suggest screening of siblings of patients with ectopic thyroid for hypothyroidism.

(Am J Dis Child 131:1264-1265, 1977)