May 1978

Gigantism With Slipped Capital Femoral Epiphysis

Author Affiliations

Departments of Pediatrics, Medicine, and Neurosurgery Wilmington Medical Center Wilmington, DE 19899

Am J Dis Child. 1978;132(5):529-530. doi:10.1001/archpedi.1978.02120300089022

Acromegalic gigantism is rare, particularly in children.1.2 This case is reported to cite the heretofore unreported, to our knowledge, association of a slipped capital femoral epiphysis with endogenous growth hormone excess, to discuss the possible cause-and-effect relationship, and to review briefly some of the subtle presenting features in gigantism.

Report of a Case.—A white girl was initially hospitalized in May 1976, at age 13 years and 11 months, for the pinning of a slipped right capital femoral epiphysis. The right leg pain began six weeks prior to admission, after the patient fell on a stairway. Some of her physical findings suggested growth hormone excess. After a short interval, she was readmitted for a pituitary evaluation and pituitary surgery.

There was a history of excess perspiration, but no history of headaches, visual difficulties, weakness, fatigability, or hirsutism. Menarche had not occurred. She had been tall since early childhood although

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