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July 1978

Myocardial Infarct in a Child With Systemic Lupus Erythematosus

Author Affiliations

From the Departments of Pathology (Drs Ishikawa, Burkholder, and Viseskul) and Pediatrics (Drs Segar, Gilbert, and Levy), University of Wisconsin Center for Health Sciences and Medical School, Madison.

Am J Dis Child. 1978;132(7):696-699. doi:10.1001/archpedi.1978.02120320056013

• An unusual case of systemic lupus erythematosus (SLE) in a young child is reported with sudden death from myocardial infarction.

The diagnosis of lupus erythematosus in this patient was made by renal biopsy at the age of 3 years. Atherosclerosis of the coronary arteries and aorta was found at autopsy with occlusion of the anterior descending branch of the left coronary artery. It is suggested that the vascular changes in this case were related to hypertriglyceridemia and prolonged prednisone therapy superimposed on a hypersensitivity vasculitis related to SLE.

(Am J Dis Child 132:696-699, 1978)