December 1978

Severe Infiltration of the Kidneys With Ultrasonic Abnormalities in Acute Lymphoblastic Leukemia

Author Affiliations

From the Departments of Pediatrics and Radiology, University of Cincinnati College of Medicine, and the Children's Hospital Medical Center, Cincinnati.

Am J Dis Child. 1978;132(12):1204-1205. doi:10.1001/archpedi.1978.02120370056012

• A 3-year-old boy with acute lymphoblastic leukemia had enlarged kidneys with impairment of renal function and hypertension as the presenting features of relapse. Ultrasound demonstrated multiple nodular areas of echolucency within enlarged kidneys that reverted to normal when the patient was in remission but then recurred during relapse. This noninvasive procedure may be useful in patients with acute lymphoblastic leukemia to determine the incidence and prognostic significance of renal involvement at the time of diagnosis, and to follow the course of those who have demonstrable changes.

(Am J Dis Child 132:1204-1205, 1978)