January 1979

Transient Neonatal Diabetes MellitusTreatment With Chlorpropamide

Author Affiliations

From the Department of Paediatrics, Dudley Road Hospital, Birmingham, England.

Am J Dis Child. 1979;133(1):65-66. doi:10.1001/archpedi.1979.02130010071012

• Nonketotic diabetes mellitus developed in a "small-for-dates" baby at the age of 6 days. The disease was controlled initially with insulin but beginning at the age of 40 days, chlorpropamide was substituted gradually for insulin over a 24-day period. Treatment was stopped at the age of 13 weeks and the baby remained well thereafter. It is suggested that chlorpropamide might be useful in the treatment of transient neonatal diabetes.

(Am J Dis Child 133:65-66, 1979)