January 1980

Prenatal Diagnosis of Genetic Disease

Author Affiliations

State University of New York Upstate Medical Center 750 E Adams St Syracuse, NY 13210


by D. C. Siggers, $9, 69 pp, 17 illus, London, Blackwell Scientific Publications, 1978.

Am J Dis Child. 1980;134(1):92. doi:10.1001/archpedi.1980.02130130074025

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This is a thin paperback with a total of 69 pages, of which 44 are text and the remainder are taken up by a list of genetic centers in Britain and the index. As the author states in his preface, the book is intended for postgraduate students in obstetrics, pediatrics, and general practice as well as for medical students, midwives, and pediatric nurses. It is oriented for use in the United Kingdom, but may be of interest to the aforementioned groups elsewhere. It would be particularly useful for the obstetrician who wants a succinct, clearly written review of current aspects of that nagging problem of prenatal diagnosis. The illustrations are good, especially the diagram that shows the risks of trisomy 21 at each year of maternal age from 34 to 41 with the use of Hook's up-to-date data. It is too elementary for medical students, who will have had much