February 1980

Autoimmune Thyroiditis With Thyrotoxicosis Eventuating in Hypothyroidism in a Short Interval

Author Affiliations

Department of Pediatrics and Rose F. Kennedy Center for Research in Mental Retardation and Human Development Albert Einstein College of Medicine 1300 Morris Park Ave Bronx, NY 10461

Am J Dis Child. 1980;134(2):206. doi:10.1001/archpedi.1980.02130140076023

Autoimmune thyroiditis may appear as thyrotoxicosis,1.2 but it usually leads to hypothyroidism, although that evolution may take years.3-6 We describe a 14½-year-old girl whose condition was in the thyrotoxic phase, who required antithyroid drugs, and who became hypothyroid in three months. The shortest interval previously described was six months.5

Report of a Case.—This 14½-year-old girl was admitted to the hospital with complaints of malaise, weight loss, sore neck, and mild fever of one week's duration, preceded by cough and rhinitis. Three days prior to admission, tender swelling was noted in the anterior side of the neck. On admission, she had a temperature of 38.9 °C, a pulse rate of 120 beats per minute and a blood pressure of 120/80 mm Hg. Her skin was warm and moist. The thyroid gland was threefold enlarged, soft and rubbery in consistency, and nontender, without local inflammatory signs. No