September 1980

Staphylococcus aureus Sepsis in Childhood Malignancy

Author Affiliations

From the Department of Pediatrics, University of Washington, Children's Orthopedic Hospital and Medical Center, Seattle. Drs J. S. Miser and A. W. Miser are now at Ohio State University, Columbus Children's Hospital, Columbus, Ohio.

Am J Dis Child. 1980;134(9):831-833. doi:10.1001/archpedi.1980.02130210015005

• Forty-five episodes of Staphylococcus aureus septicemia occurred in 44 children with malignant neoplasms over a seven-year period. The most frequent findings at diagnosis were fever, neutropenia, and an active malignant process. Twenty-six (58%) of 45 episodes had a primary focus of infection. Multiple-organism sepsis occurred four times; three episodes were fatal. Only one patient with single-organism S aureus sepsis died (a mortality of 2%). Direct infectious complications occurred in nine (20%) of 45 episodes. Endocarditis and osteomyelitis were not seen as complications of S aureus sepsis.

(Am J Dis Child 134:831-833, 1980)