• A 3-year-old girl had the typical features of visceral larva migrans syndrome, including hypereosinophilia, recurrent pulmonary infiltrates, and elevated serum IgG, IgE, and isohemagglutinin titers. A marked mitogenic response of her cultured lymphocytes to Toxocara antigen but not to Ascaris antigen was found. A neutrophil chemotactic abnormality to Escherichia coli culture filtrates and zymosan-activated sera was also demonstrated, which partially corrected after she was treated with diethylcarbamazine citrate.
(Am J Dis Child 134:845-847, 1980)
Caldwell K, Lobell M, Coccia PF. Mitogenic Response to Toxocara Antigen and Chemotactic Defect in Visceral Larva Migrans. Am J Dis Child. 1980;134(9):845-847. doi:10.1001/archpedi.1980.02130210029008