January 1981

Transient Protein-Losing Enteropathy and Enlarged Gastric Rugae in Childhood

Author Affiliations

From the Tucson Hospitals Medical Education Program (Dr Stillman), and the Departments of Pediatrics (Drs Stillman, Sieber, and Manthei) and Internal Medicine (Dr Pinnas), University of Arizona College of Medicine, Tucson.

Am J Dis Child. 1981;135(1):29-33. doi:10.1001/archpedi.1981.02130250017007

• Data on two patients with massive but transient protein-losing enteropathy due to gastric disease suggest that antibody-mediated allergic reactions may have been responsible for the clinical picture. The majority of patients described in the literature have had evidence of a preceding or concomitant viral infection, and three of these have had evidence of infection with cytomegalovirus. Recovery occurred relatively rapidly in all patients without sequelae. The syndrome may be a variant of eosinophilic gastroenteritis.

(Am J Dis Child 135:29-33, 1981)