February 1981

Hemodialysis in the Premature Infant

Author Affiliations

Department of Pediatrics; Department of Medicine University of Minnesota Hospitals 420 Delaware St, SE Minneapolis, MN 55455

Am J Dis Child. 1981;135(2):178-180. doi:10.1001/archpedi.1981.02130260066020

Progress in neonatal medicine1 has created an increased demand for life-support systems for the critically ill infant, in whom acute renal failure is a common complication. We have modified techniques for hemodialysis for use in the small child.2 We describe hemodialysis of a 2-kg infant and discuss the indications for hemodialysis in small babies.

Report of a Case.—The patient was one of female twins, with a birth weight of 2,100g at 34 weeks' gestation. She experienced a paroxysmal cough, tachypnea, and slightly inflamed conjunctivae at 4 weeks of age. The serum creatinine level was 0.3 mg/dL. Initial viral and bacterial cultures were negative.

She subsequently experienced hyponatremia, focal seizures, and Coombs-negative hemolytic anemia, and hypertension, oliguria, and thrombocytopenia developed, with rising BUN and creatinine levels. At 7 weeks of age, she weighed 2,600g and was edematous and cachectic. The serum potassium concentration was 6.2 mEq/L and the

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