April 1981

Nail Hyperpigmentation Secondary to Therapy With Doxorubicin

Author Affiliations

From the Divisions of Dermatology (Drs Giacobetti and Esterly) and Hematology (Dr Morgan), Department of Pediatrics, Northwestern University Medical School, Chicago.

Am J Dis Child. 1981;135(4):317-318. doi:10.1001/archpedi.1981.02130280007003

• Hyperpigmentation of the fingernails can occur during therapy with doxorubicin (Adriamycin). Two patterns are common: diffuse, and transversely banded. The pigment is believed to be melanin, and both patterns disappeared with discontinuation of therapy and subsequent nail growth.

(Am J Dis Child 1981;135:317-318)