June 1981

Review of Coccidioidomycosis in Immunocompromised Children

Author Affiliations

From the Department of Pediatrics, Division of Infectious Diseases and Immunology, University of Rochester Medical Center, Rochester, NY. Dr MacDonald is a recipient of an Ontario Ministry of Health Fellowship.

Am J Dis Child. 1981;135(6):553-556. doi:10.1001/archpedi.1981.02130300053018

• Only 13 cases of coccidioidomycosis in immunocompromised children have been previously reported. Of the reported cases, seven children had extrapulmonary involvement and all died, while the six children with disease limited to the lungs survived the infection. A leukemic child who was treated for disseminated coccidioidomycosis and survived is described. Reviews of immunocompromised adult patients with coccidioidomycosis suggest factors that might be related to dissemination. Similar factors for immunocompromised children could not be defined, thus suggesting the need for more information regarding coccidioidomycosis.

(Am J Dis Child 1981;135:553-556)