December 1981

A Study of the Nutritional Status of Pediatric Cancer Patients

Author Affiliations

From the Stanford University Medical Center, Stanford, Calif (Dr Donaldson); Children's Hospital Medical Center and Sidney Farber Cancer Institute, Boston (Drs Suskind and Jaffe); M. D. Anderson Hospital and Tumor Institute, Houston (Dr vanEys); and the National Cancer Institute, Bethesda, Md (Drs Wesley and DeWys).

Am J Dis Child. 1981;135(12):1107-1112. doi:10.1001/archpedi.1981.02130360015007

• The records of 455 children were reviewed to investigate the relationship of nutritional status at time of first referral to various measurements of disease and survival. Initial symptoms of weight loss, anorexia, fatigue, and early satiety were all directly correlated. Serum albumin level and nutritional status were not directly correlated. Likewise, there was no direct relationship between performance status and nutritional status. However, higher values of serum albumin were associated with better performance status. Nutritional status was directly related to freedom from relapse among children with solid tumors whether they had localized or nonlocalized disease. In addition, improved survival was related to good nutritional status for children with localized disease, whereas those with advanced disease had a poorer survival regardless of their nutritional status. Nutritional status appears to have prognostic implications among children with cancer.

(Am J Dis Child 1981;135:1107-1112)