Hyperprolactinemia, galactorrhea, testicular enlargement, sexual precocity, and hypertrophy of the labia have been associated with primary hypothyroidism.1-6 We describe a 13-year-old girl with hypothyroidism who was referred to an endocrine clinic for evaluation of ambiguous genitalia.
Report of a Case.—A 13-year-old girl was referred to a pediatric endocrine clinic for evaluation of ambiguous genitalia. She had been adopted in infancy and was the product of an uncomplicated gestation. Her weight at birth had been 3,500 g and her length, 47.5 cm. Her physical and mental development had been normal until the age of 8 years, when her adoptive parents noted onset of poor linear growth, tiredness, intolerance of cold, and rough skin. Two years before coming to the clinic she had gained 4 kg during a period of 12 months. Since then her weight had remained steady. For the past two years, she had experienced increasing difficulty in
RAMAYYA MV, RUVALCABA RHA, KELLEY VC. Hypothyroidism and Apparent 'Ambiguous Genitalia'. Am J Dis Child. 1982;136(5):464-465. doi:10.1001/archpedi.1982.03970410082021