Pyloric stenosis is a well-known, relatively frequent abnormality usually occurring in the first few weeks of life. Its occurrence in twins has been well documented.1-3 However, to our knowledge, this is the first report in monozygous triplets and only the second in triplets generally.4
Report of a Case.—Male triplets were born of an uncomplicated pregnancy two weeks prematurely. Neither parent had pyloric stenosis or any knowledge of other affected family members. The mother was 28 years old, the father 32 years old. Monozygosity was established by the presence of a single chorion. Birth weights were 1,960 g, 1,760 g, and 1,790 g in order of presentation.
The first of the triplets was seen at 8 weeks of age with a three-day history of nonbilious vomiting. He was promptly referred for upper gastrointestinal (GI) tract study and the diagnosis of pyloric stenosis was made. The roentgenographic findings were
GILLESPIE JC, PETERSON GH, LEHOCKY R, SHEARER L. Occurrence of Pyloric Stenosis in Triplets. Am J Dis Child. 1982;136(8):746-747. doi:10.1001/archpedi.1982.03970440090030