A 4-year-old child has been followed up in an oncology clinic for 18 months for chemotherapy and radiation therapy for stage III Wilms' tumor. As part of her routine clinic visit, a chest roentgenogram is obtained, and a new finding, a nodule, is observed in the right upper lung field. The pediatrician/oncologist has to decide whether the lung lesion should be considered to be metastatic Wilms' tumor or something else. Soon, there may be a new option, ie, nuclear magnetic resonance, which has the potential for distinguishing between benign and malignant tissue. If the lesion is benign, probably a histoplasmoma, nothing needs to be done. On the other hand, if the lesion is malignant, there are profound implications in terms of treatment plans.
HELLER RM, PARTAIN CL, JAMES AE. Implications of Nuclear Magnetic Resonance Imaging for the Pediatrician. Am J Dis Child. 1982;136(12):1045-1046. doi:10.1001/archpedi.1982.03970480011001