[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.161.178.52. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
January 1983

The Impact of Cranial Irradiation on the Growth of Children With Acute Lymphocytic Leukemia

Author Affiliations

From the Department of Pediatrics, University of North Carolina, Chapel Hill.

Am J Dis Child. 1983;137(1):37-39. doi:10.1001/archpedi.1983.02140270033012
Abstract

• Heights, height velocities, weights, and weight velocities were measured serially in 21 patients with acute lymphocytic leukemia (ALL) who had survived three to five years in continuous complete remission. These patients were assigned randomly to treatment regimens that varied according to whether cranial irradiation was used. Patients receiving cranial irradiation had lower height velocities during therapy than normal subjects and patients not receiving cranial irradiation. Twenty-two other children with ALL, who were irradiated but not randomized, exhibited similar alterations in growth. These results indicate that cranial irradiation, and not leukemia or antileukemic chemotherapy, causes reduced growth.

(Am J Dis Child 1983;137:37-39)

×