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Lead Poisoning in Infancy An 8-month-old female infant was admitted to the Babies' Hospital of Baltimore with persistent convulsions. Symptoms began one day before admission with fretfulness, pallor, and poor nursing. Physical evidence of rickets and right-sided facial weakness were noted. Anemia and basophilic stippling were present. Spinal fluid pressure was increased with increased cells and a positive globulin reaction. No tests for lead could be done. It was found that the mother had been using "diachylon compound" containing lead acetate for a rash on her nipples during the preceding eight weeks. The baby responded slowly throughout two months. At 15 months, she was not walking and could not talk. The literature on congenital and infant lead poisoning is reviewed.—L. Emmett Holt, Jr, MD, Baltimore (March 1923;25:229-233).
60 YEARS AGO IN THE AJDC. Am J Dis Child. 1983;137(3):235. doi:10.1001/archpedi.1983.02140290027007