• A model is proposed for analyzing the many extrinsic and intrinsic factors that might affect the incidence of low-birth-weight (LBW) infants (<2,501 g) adversely in populations of variable socioeconomic status (SES). The model provides for categorizing all mothers either into one of four broad categories of extrinsic factors or into a normal group, free of all extrinsic factors. Application of the model in a prospective study of 972 infants showed that the incidence of LBW infants was low in normal pregnancies and significantly higher in the categories of extrinsic factors, that SES had a limited role in the birth of LBW infants, and that intrinsic factors had an almost negligible adverse effect if properly controlled.
(Am J Dis Child 1983;137:323-327)
Miller HC. A Model for Studying the Pathogenesis and Incidence of Low-Birth-Weight Infants. Am J Dis Child. 1983;137(4):323-327. doi:10.1001/archpedi.1983.02140300005002