• The incidence of clinically detectable patent ductus arteriosus (PDA) in a group of preterm infants whose birth weights were less than 2,000 g was compared with that of a similar group of infants whose mothers received antenatal glucocorticoids. A PDA was diagnosed on the basis of a typical heart murmur, increased precordial activity, and bounding peripheral pulses beyond the third day of life. Whereas 14 (44%) of 32 infants who were not exposed to antenatal glucocorticoids showed evidence of a PDA, only one (6.5%) of 15 infants whose mothers received antenatal glucocorticoids had similar findings. The incidence of ruptured membranes (>72 hours), the number of infants who were small for gestational age, and clinical management of the infants in the two groups were similar.
(Am J Dis Child 1983;137:336-338)
Waffarn F, Siassi B, Cabal LA, Schmidt PL. Effect of Antenatal Glucocorticoids on Clinical Closure of the Ductus Arteriosus. Am J Dis Child. 1983;137(4):336-338. doi:10.1001/archpedi.1983.02140300018005