November 1983

Nephrotic Syndrome After Mumps Virus Infection

Author Affiliations

University of Lund General Hospital Malmö, Sweden

Am J Dis Child. 1983;137(11):1126. doi:10.1001/archpedi.1983.02140370082026

Renal involvement in patients with mumps virus infections has been investigated in a series of studies by Utz et al.1-4 Viruria, transient hematuria, proteinuria, and reduced creatinine clearance were noted in each of 20 patients with mumps confirmed by laboratory findings. These studies suggested a prolonged viral infection of the urinary tract and viral multiplication within the kidneys. Instances of concurrent mumps virus infections and nonfatal nephritis have also been reported,5,6 although in these cases, concomitant poststreptococcal glomerulonephritis could not be excluded. We describe a patient in whom nephrotic syndrome developed after mumps virus infection was confirmed by serologic tests.

Report of a Case.—A 5-year-old girl who had previously been healthy was admitted to a hospital two weeks after the onset of parotitis. Insidious swelling was noted around her eyes, ankles, and feet. The output of urine had decreased gradually. Her BP was normal. The following abnormal