December 1983

Nifedipine in Hypertensive Emergencies of Children

Author Affiliations

From the Hacettepe Children's Hospital, Ankara, Turkey.

Am J Dis Child. 1983;137(12):1162-1165. doi:10.1001/archpedi.1983.02140380022007

• We studied the acute antihypertensive effect of sublingually administered nifedipine in 21 patients with different clinical diagnoses. Nifedipine lowered systolic and diastolic BP from 181 ± 18 and 136 ± 21 mm Hg to 132 ± 15 and 98 ± 17 mm Hg, respectively, after 30 minutes, and produced a slight increase in heart rate. This is the first known study of administration of nifedipine for acute hypertension in children.

(Am J Dis Child 1983;137:1162-1165)