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July 1984

Neonatal Lupus Erythematosus

Author Affiliations

From the Dermatology Unit, University of Rochester (NY) Medical Center (Dr Lane); and the Department of Dermatology, The Johns Hopkins Medical Institutions, Baltimore (Dr Watson).

Am J Dis Child. 1984;138(7):663-666. doi:10.1001/archpedi.1984.02140450045013

• Three infants with neonatal lupus erythematosus (LE) had characteristic sharply marginated erythematous papules and plaques without congenital heart block. Two of the infants were definitely photosensitive, while the third infant's eruption began on a photoexposed area. All three infants and their mothers were positive for Ro Sjögren's syndrome A antigen (SSA) antibody. These three infants have additional evidence supporting the concept that transplacental passage of Ro (SSA) antibody is a serologic marker for neonatal LE.

(AJDC 1984;138:663-666)