December 1984

Weaver-Smith SyndromeA Case Study With Long-term Follow-up

Author Affiliations

From the Departments of Pediatric Neurology (Drs Amir and Silverberg-Shalev) and Pediatrics (Dr Gross-Kieselstein), Bikur Cholim Hospital; the Department of Endocrinology and Metabolism, Shaare-Zedek Hospital (Dr Hirsch); and the Department of Radiology, Hadassah-Hebrew University Hospital (Dr Lax), Jerusalem.

Am J Dis Child. 1984;138(12):1113-1117. doi:10.1001/archpedi.1984.02140500019006

• We studied a 6-year-old-boy who was followed up from infancy and who had Weaver-Smith syndrome (WSS), a syndrome characterized by excessive growth, dysmorphic facies, psychomotor retardation, and specific radiologic features. The child's height and bone age were far greater than his chronological age and he demonstrated hypothyroidism at the age of 6 years, but had no endocrinologic abnormalities when he was examined at 11 months of age and again at 4 years of age. We compared the clinical and laboratory features of this child with all other reported cases of WSS.

(AJDC 1984;138:1113-1117)