December 1984

Type 2 Corticosterone Methyloxidase Defect in a 2-Year-Old Iranian Jewish Child

Author Affiliations

Division of Pediatrics Scripps Clinic and Research Foundation 10666 N Torrey Pines Rd La Jolla, CA 92037

Am J Dis Child. 1984;138(12):1154. doi:10.1001/archpedi.1984.02140500058020

Sir.—The article "Selective Hypoaldosteronism in Infancy" by Curtis et al1 brought back to mind a patient who subsequently became one of the cases cited by Rosler et al2 in their review article on this subject.

Report of a Case.—A male infant was the product of a full-term, uncomplicated pregnancy of Iranian Jewish parents. Both parents were 26 years of age. There was consanguinity in the family; the maternal great-grandmother was the paternal grandmother's sister. A previous male sibling was normal and was 4 years old at the time of the infant's birth.

The infant was a poor feeder from birth with chronic constipation and was admitted to the University of California—San Diego Hospital at 3½ months of age for failure to thrive. The results of his physical examination were normal, except for weight below the third percentile. Laboratory findings, including complete blood cell count, ESR, blood

First Page Preview View Large
First page PDF preview
First page PDF preview