• The role of human enteric coronaviruses in infantile gastroenteritis is controversial. We detected coronavirus-like particles in the intestinal contents and within the epithelial cells of the ileum in a 15-month-old infant who had postmortem evidence of severe enteritis. Ultrastructural findings consistent with in vivo coronavirus replication in the human small intestine support a causative role for this agent in gastroenteritis.
Rettig PJ, Altshuler GP. Fatal Gastroenteritis Associated With Coronaviruslike Particles. Am J Dis Child. 1985;139(3):245-248. doi:10.1001/archpedi.1985.02140050039017