Sir.—We have read the article "Torulopsis glabrata Sepsis Appearing as Necrotizing Enterocolitis and Endophthalmitis" with interest.1 We have previously described a 2-month-old male infant with chronic granulomatous disease who died with systemic Toruplosis.2
Although chronic granulomatous disease is usually transmitted as a sexlinked recessive trait with clinical manifestations seen only in boys, very similar conditions have been seen in young girls associated with systemic fungal infections, albeit less frequently.3 In view of the extreme rarity of Torulopsis as a pathogen in young children, it might be useful to investigate the immune status of this young girl's family.
ORSON JM, GRECO RG. Chronic Granulomatous Disease and Torulopsis Infections. Am J Dis Child. 1985;139(6):545. doi:10.1001/archpedi.1985.02140080015011