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June 1985

Chlamydial Ophthalmia NeonatorumThe Dilemma of Diagnosis and Treatment

Author Affiliations

Clinical Investigation Section Division of Sexually Transmitted Diseases Centers for Disease Control 1600 Clifton Rd Atlanta, GA 30333

Am J Dis Child. 1985;139(6):550-551. doi:10.1001/archpedi.1985.02140080020022

Over the last 25 years, Chlamydia trachomatis has emerged as one of the major sexually transmitted pathogens of our time. First, it appears to be highly prevalent; the organism has been cultured in 2% to 24% of pregnant women1 and from over 15% of sexually active adolescents.2,3 These samples represent a cross section of sexually active American women of childbearing age, and the prevalences quoted are substantially higher than those for gonorrhea in the same groups. Second, although linked to clinical cervicitis in women and urethritis in men, a large proportion of infections are asymptomatic. Third, infection with C trachomatis can have serious sequelae, primarily pelvic inflammatory disease, endometritis, and involuntary infertility in women. A distressing fact is that in many women the chlamydial pelvic disease leading to infertility has been either asymptomatic or subclinical. Fourth, although the jury is still out, it may be causal in a

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