• During one year 200 healthy, full-term infants were followed up prospectively for frequency of infection. Infants were categorized by mode of feeding—breast, breast-and-bottle, or bottle—and were subcategorized by location of care and by number of siblings in the home. The average number of infections in infants fed in a day-care or sitter location was 35% greater than that in infants fed at home. The mode of feeding had no bearing on the frequency of infection.
Agre F. The Relationship of Mode of Infant Feeding and Location of Care to Frequency of Infection. Am J Dis Child. 1985;139(8):809-811. doi:10.1001/archpedi.1985.02140100071033