• A patient with fully expressed, sporadic ectrodactyly, ectodermal dysplasia, and cleft lip and/or palate (EEC) syndrome with renal involvement is presented; descriptions of four similar patients were found in the literature. Based on these patients, we suggest that the renal involvement is a form of dysplasia secondary to fetal urinary tract obstruction. We emphasize the importance of searching for a urinary tract anomaly in patients with this uncommon syndrome.
London R, Heredia RM, Israel J. Urinary Tract Involvement in EEC Syndrome. Am J Dis Child. 1985;139(12):1191-1193. doi:10.1001/archpedi.1985.02140140025017