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May 1986

Improved Growth of Three Uremic Children by Nocturnal Nasogastric Feedings

Author Affiliations

From the Divisions of Nephrology (Drs Strife and Clardy and Ms Quinlan) and Gastroenterology (Ms Davey), Children's Hospital Research Foundation, Cincinnati; and the Department of Dietetics and Nutrition, Children's Medical Center, Dayton, Ohio (Ms Mears).

Am J Dis Child. 1986;140(5):438-443. doi:10.1001/archpedi.1986.02140190048022

• Three children with high-output renal insufficiency (estimated creatinine clearance, 20 to 25 mL/min/1.73 sq m) and linear and ponderal growth retardation were administered nocturnal nasogastric (NG) feedings at home by trained parents. The NG feedings were initiated at 50 kcal/kg/night and increased as needed to establish and maintain weight gain. Nocturnal feedings were continued for 13.5,16, and 11 months, respectively. Improved caloric intake reestablished the velocity of weight gain from less than 5% to greater than 95% in each patient. Linear growth velocity improved from less than 5% in two patients and 40% in one patient to greater than 95% in two patients and 80% in the third patient. No change was observed in serum creatinine, electrolyte, calcium, or phosphorus levels. The serum urea nitrogen level remained below 100 mg/dL. Ensuring adequate caloric intake by nocturnal NG feedings, in addition to standard therapy, improved both ponderal and linear growth velocity.

(AJDC 1986;140:438-443)