August 1986

Sweet's Syndrome With Multifocal Sterile Osteomyelitis

Author Affiliations

From the Department of Pediatrics, University of Tennessee Center for the Health Sciences, and the LeBonheur Children's Medical Center, Memphis.

Am J Dis Child. 1986;140(8):817-818. doi:10.1001/archpedi.1986.02140220099042

• Sweet's syndrome is a rare condition characterized by fever, leukocytosis, dense dermal infiltration of leukocytes, and painful indurated cutaneous plaques. We describe a 23-month-old male infant with the typical cutaneous manifestations of Sweet's syndrome and painful extremities that limited ambulation. Evaluation revealed multifocal sterile osteomyelitis of both tibia. After the institution of systemic corticosteroid therapy, the patient's symptoms resolved, and bone scans normalized. After one year of follow-up, the patient has intermittent recrudescences that resolve during corticosteroid therapy. Sterile multifocal osteomyelitis represents another clinical manifestation of Sweet's syndrome.

(AJDC 1986;140:817-818)