September 1986

Bacterial Meningitis in Arizona American Indian Children

Author Affiliations

From the Department of Pediatrics, Phoenix Indian Medical Center (Drs Yost, Bustamante, Ellison, Hargrave, and Randall), and the Department of Pediatric Neurology, Phoenix Children's Hospital (Dr Kaplan).

Am J Dis Child. 1986;140(9):943-946. doi:10.1001/archpedi.1986.02140230113047

• Bacterial meningitis is a major cause of morbidity and mortality in Arizona infants and children. A retrospective review of 102 cases of meningitis occurring in the American Indian population documents the prevalence of the Haemophilus influenzae organism with a peak incidence in the first year of life. The rate of H influenzae resistance to ampicillin was 16%. Overall morbidity and mortality rates are comparable with reviews of diverse populations, but there is an exceptional mortality and prolonged hospitalization in patients less than 1 year of age. The development of an efficacious vaccine against H influenzae may substantially reduce and prevent this cause of meningitis.

(AJDC 1986;140:943-946)