October 1987

--Polycythemia in Hypothyroid Infants

Author Affiliations

From the Department of Pediatrics, Cornell University Medical College, New York (Drs Weinblatt, Fort, and Kochen); the Division of Pediatric Hematology/Oncology, North Shore University Hospital, Manhasset, NY (Drs Weinblatt and Kochen); and the Department of Pediatric Pulmonology, Mount Sinai Hospital, New York (Dr DiMayio).

Am J Dis Child. 1987;141(10):1121-1123. doi:10.1001/archpedi.1987.04460100099038

• Twenty-three infants with congenital hypothyroidism were evaluated for the presence of anemia. Though no patient was found to be anemic, six (26%) had elevated hemoglobin levels, some with significant elevations. Pathogenesis of this finding is unclear, as none of the effects of thyroxine on erythropoiesis previously described would result in polycythemla. Pediatricians caring for hypothyroid infants should be aware of this association so as to be better prepared for any complication related to the hyperviscosity syndrome.

(AJDC 1987;141:1121-1123)