A 12-year-old black boy was admitted to the hospital with gross hematuria that included clots, dysuria, and abdominal and back pain. He had a history of hemoglobin SA disease (HbSA) (sickle cell trait) and recurrent episodes of painless gross hematuria for nine months. His blood pressure was 140/92 mm Hg, but physical findings were normal. Specifically, no abdominal mass was palpable. Urinary laboratory findings were as follows: specific gravity, 1.014; dipstick protein, 3+; and dipstick blood, 3+. An intravenous urogram (Fig 1) and a renal arteriogram (Fig 2) were obtained. Urinary cytologic examination showed nonspecific, atypical red blood cells. Exploratory laparotomy was performed.
Denouement and Discussion
Renal Cell Carcinoma in a Child With Hemoglobin SA Disease
Exploratory laparotomy confirmed the presence of a right renal neoplasm that required nephrectomy. Histopathologic analysis of the neoplasm revealed papillary renal cell carcinoma. Renal cell carcinoma is rare, but it has been reported with increasing
Kawanami T, Young LW, Wood BP. Radiological Case of the Month. Am J Dis Child. 1988;142(7):783-784. doi:10.1001/archpedi.1988.02150070097035