October 1988

Thyroid Scanning, Ultrasound, and Serum Thyroglobulin in Determining the Origin of Congenital Hypothyroidism

Author Affiliations

Centre Régional de Dépistage des Maladies Métaboliques de l'Enfant Faculté de Médicine Place de Verdun F-59000 Lille France

Am J Dis Child. 1988;142(10):1023. doi:10.1001/archpedi.1988.02150100017010

Sir.—Muir et al1 recently presented results of different diagnostic procedures to determine the cause of con

Comparison Between Our Results and Those of Muir et al1 Concordance Between Ultrasound Examination and Scan by Study, % Diagnosis Based on the Radioactive Iodine Muir et al1 Our Study 123 Scanning Result (n = 50) (n=78) Athyrotic glands 66.6 72.7 Ectopic glands 0.0 73.0 Normally located glands 93.4 95.8 genital hypothyroidism (CH).

We would like to comment on their conclusions in regard to our experience with radioactive iodine 123 scanning and cervical ultrasound (US) in 80 hypothyroid patients. An iodine 123 scan was performed at the initial visit (mean age, 19 days) and US examination was performed at 4 months of age. Cervical US examinations were performed and reviewed by the same interpreter, who was "blinded" to the result of the scan, as in the work of Muir et al.1

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