[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.205.0.26. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
November 1988

LATE EFFECTS OF CHILDHOOD CANCER

Am J Dis Child. 1988;142(11):1147. doi:10.1001/archpedi.1988.02150110025011

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Abstract

Twenty-five years ago the outlook for children with cancer was poor. Fewer than 25% survived for three or more years. Rare exceptions to this grim experience included children with localized and totally resected Wilms' tumor and neuroblastoma and with stage I Hodgkin's disease, and the occasional patient with acute lymphoblastic leukemia (ALL). Major advances in diagnosis and treatment have increased cure rates to over 50% for all major childhood cancers except acute nonlymphoblastic leukemia, malignant brain tumors, and selected metastatic (stage IV) solid tumors. Major contributors to this success are the effective use of multimodality therapy, improved supportive care, and, more recently, the identification of clinical and biological prognostic factors that determine the relative intensity and duration of treatment.

It has been estimated that by 1990, 0.1% of all adults (1:1000) will be cured patients who had had pediatric cancer. Thus, physicians caring for children, adolescents, and young adults should be

First Page Preview View Large
First page PDF preview
First page PDF preview
×