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November 1988

Sample Size

Author Affiliations

From the Los Lunas (NM) Hospital and Training School and the Department of Pediatrics, University of New Mexico School of Medicine, Albuquerque.

Am J Dis Child. 1988;142(11):1213-1215. doi:10.1001/archpedi.1988.02150110091026

• Before undertaking a research comparison, investigators may wish to estimate the sample sizes needed to assure that the research is feasible and is worth the effort and expense. Such calculations require several decisions by the researchers: (1) the acceptable level of the type I error (P value), (2) the desired power of the test, (3) the difference between the samples that is considered to be important, and (4) the variability expected among the values to be studied. Some recipes for estimating approximate sample sizes are suggested.

(AJDC 1988;142:1213-1215)