To determine the etiologic agents in children with acute lower respiratory infection.
A survey of a series of patients.
General pediatric hospital serving an urban population with and without referrals in Helsinki, Finland. Participants: 135 Finnish children aged 2 months to 15 years (mean, 1.75 years), with clinically defined acute lower respiratory infection (with difficulty of breathing), or found to ave fever and a pneumonic infiltrate on chest roentgenogram.
Consecutive sample on voluntary basis.
Of 121 children with adequate samples, an etiologic diagnosis could be established in 84 (70%): 30 (25%) had bacterial, 30 (25%) viral, and 24 (20%) mixed infections. Antibody assays alone identified the agent in 91% of positive cases.
Bacterial infections are common but generally underestimated in acute lower respiratory infection; serologic methods add significantly to their detection.(AJDC. 1991;145:618-622)
Nohynek H, Eskola J, Laine E, Halonen P, Ruutu P, Saikku P, Kleemola M, Leinonen M. The Causes of Hospital-Treated Acute Lower Respiratory Tract Infection in Children. Am J Dis Child. 1991;145(6):618-622. doi:10.1001/archpedi.1991.02160060036016