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In Reply.—Dr Goldenring has raised a legitimate point. We were aware of the association of family history in gallbladder disease; however, due to the fact that our work was based mainly on reviews of medical records, we could not draw any definitive conclusion. Although family history was not mentioned in many of the records, that does not mean that it did not exist. In only one case was there a positive family history for cholelithiasis, and that case was part of the idiopathic group. Further studies are needed to determine whether family history is more associated with cholelithiasis in children than in adults, particularly in the idiopathic group.
REIF S. Importance of Family History in Adolescent Gallbladder Disease-Reply. Am J Dis Child. 1992;146(1):12. doi:10.1001/archpedi.1992.02160130014005