September 1992

The Development of Thyroid Storm in a Child With McCune-Albright Syndrome After Orthopedic Surgery

Author Affiliations

From the Departments of Anesthesia/Critical Care (Dr Lawless), Pediatrics (Dr Reeves), and Orthopedics (Dr Bowen), Alfred I. duPont Institute, Wilmington, Del, and Thomas Jefferson University School of Medicine, Philadelphia, Pa.

Am J Dis Child. 1992;146(9):1099-1102. doi:10.1001/archpedi.1992.02160210101033

• Objective.  —To report a case of thyroid storm that developed in a child with McCune-Albright syndrome after orthopedic surgery. The development of thyroid storm has not previously been described after surgery in a child.

Design.  —Descriptive case report.

Setting.  —Pediatric intensive care unit.

Participant.  —Patient with McCune-Albright syndrome who developed thyroid storm.

Selection Procedures and Interventions.  —Clinical features and treatment of thyroid storm are described. A highly sensitive immunochemiluminometric thyroid-stimulating hormone assay to help diagnose hyperthyroid states is also described.

Conclusions.  —Before all operative procedures, children at high risk for thyroid dysfunction, including patients with McCune-Albright syndrome, should be screened and observed closely for the development of thyroid storm.(AJDC. 1992;146:1099-1102)